Prostate medication12/24/2023 Side Effects of Alpha Blockers: Orthostatic Hypotension, Falls and Fractures: Researchers now think there are other mechanisms in play but they haven’t completely figured out what they might be. It was once thought that relaxing smooth muscle in the prostate with alpha blockers would make peeing easier. This leads to enhanced vasodilation, improved blood flow and lower blood pressure. By blocking the action of the neurotransmitter norepinephrine (aka noradrenaline) small arteries cannot constrict as they normally would. ![]() ![]() Hytrin got the green light in 1987 for high blood pressure.Īlpha blockers are thought to work to lower blood pressure by relaxing smooth muscles that surround blood vessels. Their predecessor, prazosin ( Minipress), was approved in the early 1980s to help control hypertension. The first-generation drugs in this class (doxazosin and terazosin) were originally developed to lower blood pressure. ![]() If your drug has “ OSIN” at the end of its name there is a good chance you are taking what is called an alpha blocker. History and Complications from Alpha-Blockers: What they may not realize is that there could be unexpected problems with prostate drugs. A lot of men who never contemplated problems peeing are now taking drugs to help them urinate: tamsulosin ( Flomax, Jalyn), alfuzosin ( Uroxatral), silodosin ( Rapaflo), doxazosin ( Cardura) and terazosin ( Hytrin). Aging baby boomers are discovering that they too are experiencing the ailments of their fathers and grandfathers.
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